Anti-aging effects of oligomeric proanthocyanidins isolated from persimmon fruits
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چکیده
منابع مشابه
Anti-aging effects of oligomeric proanthocyanidins isolated from persimmon fruits.
Senescence-accelerated mouse prone/8 (SAMP8), a murine model of accelerated senescence, shows age-related deficits in learning and memory. The oral administration of oligomers improved spatial and object recognition impairment in SAMP8. The expression of phosphorylated neurofilament-H was significantly elevated in the hippocampal CA1. This indicates that oligomers induce an increase in the dens...
متن کاملRole of oligomeric proanthocyanidins derived from an extract of persimmon fruits in the oxidative stress-related aging process.
Many researchers have focused on the oligomeric form of proanthocyanidins with a lower level of polymerization found in foodstuffs such as grape seeds and blackberries. The present study indicated that the oral administration of oligomers isolated from persimmon fruits extended the lifespan of senescence-accelerated mouse prone/8 (SAMP8), a murine model of accelerated senescence. On the other h...
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Carotenoids in the peel and the flesh of persimmon fruit were identified, and the contents of carotenoids in the fleshes of 46 different persimmon cultivars were analyzed. The results indicated that 31 specific carotenoids were detected in both cultivars of persimmons, among which nine specific carotenoids were characterized. β-cryptoxanthin was the most abundant carotenoid among all individual...
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Ethanolic extract of durian seeds was fractionated by reverse phase flash column chromatography and the fractions characterized by electrospray ionization mass spectroscopy. Among a few unknown compounds collected, oligomeric proanthocyanidins (OPCs) were found to be one of the main compounds. Based on this result, the OPCs were purified the first time from the durian seeds using standard proce...
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The present study was carried out to evaluate the promising potential of polymers and oligomers from proanthocyanidins of persimmon peel as antioxidants and therapeutic agents for diabetes. Both polymers and oligomers showed the scavenging effect of 2,2-diphenyl-l-picrylhydrazyl, with IC50 values of 4.35 and 2.41 microg/mL, respectively, and they also showed a protective activity against protei...
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ژورنال
عنوان ژورنال: Drug Discoveries & Therapeutics
سال: 2011
ISSN: 1881-7831,1881-784X
DOI: 10.5582/ddt.2011.v5.3.109